Vertex To Acquire Crinetics Pharmaceuticals for $10 Bn 
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Vertex Pharmaceuticals has agreed to acquire Crinetics Pharmaceuticals, a San Diego, California-based bio/pharmaceutical company focused on endocrine diseases, for $10 billion.  Crinetics’ marketed medicine is Palsonify (paltusotine), a once-daily oral therapy for adults with acromegaly, a rare condition caused by a…

Novartis To Acquire Myricx Bio for $1.5 Bn 
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Novartis has agreed to acquire Myricx Bio, a privately held London-based bio/pharmaceutical company developing antibody-drug conjugates (ADCs), in a deal worth up to $1.5 billion ($1.1 billion upfront and $400 million in milestone payments).   Myricx is developing ADCs using N-myristoyltransferase inhibitor (NMTi)…

Evonik Investing $100 M in US API Mfg Facility 
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Evonik has announced a $100-million investment to strengthen its active pharmaceutial ingredient manufacturing capabilities at its Tippecanoe Labs site in Lafayette, Indiana. Over the next five years, Evonik will invest $100 million to…

Supplier News: Lonza, Olon, Bora, Thermo Fisher & More
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The latest from CDMOs, CMOs, and suppliers featuring Lonza, Olon, Bora Pharmaceuticals, Codis, Icosagen, Mikart, Thermo Fisher, Gattefosse, Just Evotec Biologics, Rentschler Biopharma and Nona Biosciences.   Chemicals/Chemical API Manufacturing * Lonza Expands HPAPI Mfg Facility* Olon Completes Expansion…

Global Briefs: AstraZeneca, Sanofi, Incyte, Ipsen, Teva & More 
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A roundup of news from the large and mid-sized bio/pharmaceutical companies featuring AstraZeneca, Sanofi, Incyte, Ispen, Teva, Boehringer Ingelheim, and Tanabe Pharma. Highlights below.   For the latest news roundup on small and…

Biotech Briefs: BridgeBio, MeiraGTx, Kalohexis & More 
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The latest from small and Emerging Pharma companies featuring BridgeBio Pharma, MeiraGTx, Kalohexis, Biocytogen, and Whitehawk Therapeutics.   For news on the large and mid-sized bio/pharmaceutical companies, see Global Briefs.  * BridgeBio Pharma Raises Nearly $1 Bn…

Merck KGaA To Acquire Bio-Techne for $11.3 Bn To Boost Life-Sciences Products Arm 
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In a move to bolster its life-sciences business, Merck KGaA has agreed to acquire Bio-Techne, a Minneapolis-Minnesota provider of life-science tools, analytical technologies, and consumables, for $11.3 billion. The acquisition is one of…

AbbVie To Acquire Apogee Therapeutics for $10.9 Bn 
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To boost its portfolio in inflammatory and immunological therapeutics, AbbVie has agreed to acquire Apogee Therapeutics, a Waltham, Massachusetts-based clinical-stage bio/pharmaceutical company, for $10.9 billion.  Apogee’s lead assets are zumilokibart, a subcutaneous half-life extended monoclonal antibody for treating atopic dermatitis (eczema) in Phase…

Sanofi Names Ex-Roche Executive as New Head of R&D
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Sanofi has named Paulo Fontoura, MD, PhD, an ex-Roche executive and currently Chief Medical Officer at Xaira Therapeutics, a South San Francisco, California-based company focused on applying AI and machine learning in drug discovery and development, as Executive Vice President,…

Supplier News: Siegfried, Evonik, Aurobindo & More 
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The latest from CDMOs, CMOs, and suppliers featuring Siegfried, Evonik, Aurobindo, Alcami, Sartorius, SK pharmteco, Shilpa Biologicals, Minaris, Argonaut Manufacturing Services, and Ensera.   Chemicals/Chemical API Manufacturing * Siegfried Opens Large-Scale API Facility* Evonik Divests Select Pharma Ingredient Production…